Engineered chimeric antigen receptor-expressing T cells for the treatment of pancreatic ductal adenocarcinoma
نویسنده
چکیده
Adoptive cell therapy with chimeric antigen receptor (CAR)-engineered T cells is under investigation as an approach to restore productive T cell immunosurveillance in patients with pancreatic ductal adenocarcinoma. Early findings demonstrate safety of this cell-based therapy and the capacity of CAR-expressing T cells to mediate anti-tumor activity as well as induce endogeneous antitumoral immune responses.
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2014